Echium amoenum, or borage is used widely in Middle East, Iran, China and India. It is one of the important medicinal herbs in traditional Iranian medicine. The active ingredients in this plant includes anthocyanidine, flavonoid aglycons and mucilage. Borage is antidepressant, antiseptic, antifungal and can help to reduce nausea, kidney inflammation, reduction of bronchitis, treatment of colds and also regenerating skin cells. It also can regulate sleeping problems.