Raw Materials

Nano Engineering Services in the Pharmaceutical Industry

At Asre Nano, by leveraging advanced nanotechnologies and modern micro- and nanoencapsulation methods—such as liposomal and phytosomal technologies—we provide specialized and efficient solutions for the pharmaceutical industry.
These services are designed to enhance therapeutic efficacy, improve drug performance, reduce side effects, and optimize production processes.

Development of Novel Drug Delivery Systems

Using liposomal, phytosomal, and exosomal technologies for slow and controlled drug release increases drug bioavailability and reduces side effects.
These systems enable gradual release of active pharmaceutical ingredients (APIs), improving treatment effectiveness and patient compliance.

Examples include:

• Iron supplements: Reduced gastrointestinal and dental side effects with enhanced bioavailability.
• Curcumin: Improved solubility, stability, and bioavailability.
• Silymarin (Milk Thistle extract): Enhanced solubility and bioavailability.
• Other compounds: Controlled and targeted release, taste masking, improved formulation flexibility, and transformation of insoluble materials (e.g., BCAA, NMN, Minoxidil, Sulforaphane, Adenosine, Vitamins, Calcium, Zinc, Probiotics, Amino Acids).

Benefits:

• Controlled and sustained drug release for prolonged therapeutic effects
• Reduced side effects through gradual release mechanisms
• Increased treatment precision with innovative drug delivery technologies

Taste and Odor Masking

Using nanoencapsulation technologies, unpleasant tastes and odors of drugs are effectively masked, minimizing oral and gastrointestinal irritation and improving patient compliance.

Examples:

• Caffeine, B Vitamins, Azithromycin: Reduction of bitterness and irritation
• Omega-3: Improved stability, odor reduction, and production of water-soluble powders
• Ibuprofen, Paracetamol, B Vitamins: Enhanced palatability and patient acceptability

Benefits:

• Elimination of unpleasant taste and odor
• Improved patient comfort and compliance
• Enhanced drug acceptance and marketability

Uniform Dispersion of Insoluble Compounds

Nanotechnologies are applied to achieve homogeneous dispersion of insoluble compounds in aqueous and organic systems.
This ensures uniform distribution of active ingredients within formulations and improves their therapeutic efficacy.

Examples:

• Curcumin and other hydrophobic compounds
• Essential oils and plant extracts (e.g., Omega-3, essential oils, natural essences)

Benefits:

• Uniform distribution of active materials
• Increased solubility and bioavailability
• Improved stability of poorly soluble drugs

Nano-Based Vaccine Adjuvant Formulations

Using natural nanoparticles such as chitosan, we design adjuvant formulations to enhance immune response and improve vaccine effectiveness.

Benefits:

• Enhanced immune response through natural nanocarriers
• Lower vaccine doses with higher efficacy
• Reduced side effects in vaccine administration

Green and Enzymatic Synthesis of Active Ingredients

Green and enzymatic synthesis methods are used to produce pharmaceutical compounds in an eco-friendly manner, minimizing pollutants and increasing process efficiency.
These methods lead to cost reduction and improved sustainability in the production of APIs.

Benefits:

• Environmentally friendly and non-polluting synthesis routes
• Reduced production costs through enzymatic methods
• Maintained stability of active ingredients during synthesis

Formulation Development and CTD Preparation

Asre Nano provides comprehensive services for formulation development of new drugs and CTD (Common Technical Document) preparation, facilitating regulatory submissions and accelerating time-to-market for pharmaceuticals.

Benefits:

• Simplified and faster regulatory approval
• Compliance with international standards and guidelines
• Accelerated market entry for new drugs

Technology Transfer and Scale-Up from Lab to Industrial Scale

We offer scale-up services for transferring production processes from the laboratory to the industrial scale using nanotechnology-based methods.
This ensures high-volume production without compromising quality, optimizing resource use and cost efficiency.

Benefits:

• Optimal utilization of production resources
• Increased production capacity with consistent quality
• Reduced manufacturing costs at industrial scale

Enhancing Drug Bioavailability

Through nanotechnology and encapsulation of active ingredients, drug bioavailability is significantly increased, improving absorption and therapeutic effectiveness while reducing required dosages.

Benefits:

• Improved bioavailability and absorption rates
• Reduced dosage and side effects
• Enhanced therapeutic performance and treatment outcomes

Knowledge-Based Product Development Services

Asre Nano offers knowledge-based pharmaceutical product development services aimed at improving the quality, efficacy, and innovation of drugs and vaccines.
These services include research and development, formulation innovation, synthesis, extraction, and processing of active ingredients using modern, efficient methods.

Benefits:

• Enhanced quality and performance of pharmaceutical products
• Support for innovation and R&D activities
• Acceleration of commercialization for knowledge-based products

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Advanced Engineering Services in Agricultural Industries

By leveraging modern nano-industrial technologies and advanced scientific methods, these services are specifically designed to optimize agricultural productivity and enhance efficiency. These solutions include coating and controlled release of nutrients, production of high value-added agricultural products, and improvement of cultivation and production processes across various agricultural sectors.

Formulation and Production of Coated and Slow-Release Micronutrients

In this process, micronutrients — including vitamins, minerals, amino acids, and other essential nutrients — are produced using advanced coating and slow-release techniques. These nutrients are released in a targeted and optimized manner over time and location, enhancing nutrient absorption and minimizing loss.

Advantages:

• Controlled and gradual release of nutrients over time
• Reduced resource waste and optimized utilization
• Improved agricultural productivity through efficient plant nutrition

Formulation of Natural Coated and Slow-Release Fertilizers and Pesticides

Through advanced formulation methods, natural fertilizers and pesticides are designed as coated and slow-release products. These approaches are especially effective in reducing environmental pollution and maintaining soil health, enabling farmers to manage resources efficiently while preserving ecological balance.

Advantages:

• Precise control of fertilizer and pesticide release to reduce environmental harm
• Enhanced efficiency with minimal input
• Lower pollution and improved sustainable agricultural performance

Production of Various Hydrogels

Hydrogels act as carriers of water and nutrients, making them highly useful in agriculture, particularly in arid and semi-arid regions. These products can retain and store water within their structure, preventing water loss and supporting plant growth — leading to improved crop yields.

Advantages:

• Enhanced water use efficiency in agriculture
• Improved plant growth under water-scarce conditions
• Reduced irrigation costs and increased productivity

Seed and Grain Coating Using Natural Nanoparticles

Seed coating with natural nanoparticles improves germination rate and reduces disease incidence. These coatings also protect seeds from adverse environmental conditions such as drought and heat stress, ultimately boosting agricultural yield.

Advantages:

• Increased seed resistance to harsh environmental conditions
• Enhanced germination rate and plant growth speed
• Reduced need for pesticides and chemical treatments

Production of High Value-Added Products from Agricultural Waste

Using advanced technologies, agricultural residues — such as straw, husks, stems, and other byproducts — are converted into high value-added products. This process not only maximizes resource utilization but also significantly reduces waste and contributes to environmental protection.

Advantages:

• Optimal utilization of agricultural resources
• Reduction of waste and creation of high value-added products
• Promotion of sustainable agriculture and environmental preservation

Development and Production of Innovative Agricultural Products to Enhance Food Security

Through scientific research and modern technologies, innovative agricultural products are designed and developed to increase crop yield and address food security challenges. These products contribute to sustainable agricultural growth while supporting domestic production and reducing dependence on imported raw materials.

Advantages:

• Increased crop yield and improved food security
• Reduced reliance on imported resources
• Support for farmers and strengthening of the national economy

Innovative Services in the Cosmetics and Personal Care Industry

By utilizing nanotechnology and encapsulation of active ingredients, innovative solutions are offered in the field of cosmetics and personal care. These services are designed to enhance product efficiency, optimize formulation and delivery processes, minimize resource waste, and improve the performance and stability of active compounds.

Production and Supply of Micro- and Nano-Encapsulated, Liposomal, Phytosomal, and Exosomal Active Ingredients

Nanotechnology enables the encapsulation of active compounds (including vitamins, proteins, amino acids, extracts, essential oils, and minerals) to enhance bioavailability and absorption efficiency — marking a significant advancement in cosmetic and personal care formulations.
In this process, active ingredients are intelligently enclosed within nano-polymeric or lipid matrices to maintain their physical and chemical properties throughout production, storage, and application. These materials can be safely used in various chemical and physical processes such as heating, baking, or UV exposure without loss of efficacy.

Advantages:

• Enhanced absorption of active compounds into the skin or body
• High bioavailability in cosmetic and personal care formulations
• Long-term stability of active ingredients in final products

Development of Topical Formulations with High Bioavailability and Absorption Based on Nanotechnology

Advanced nano-based cosmetic formulations allow consumers to benefit optimally from active ingredients such as vitamins, antioxidants, and fatty acids. Upon application to the skin, these formulations deliver active compounds uniformly and efficiently to deeper layers.

Advantages:

• Faster and more effective action of topical formulations
• Protection of active ingredients from environmental degradation
• Improved penetration and stability of active compounds in nano-formulations

Production and Supply of Natural and Plant-Based Actives, Extracts, Essential Oils, Fragrances, and Pigments in Powder, Granule, and Microsphere Forms

Plant extracts and essential oils are produced through advanced extraction technologies such as Supercritical CO₂ Extraction, which helps preserve the bioactive properties of the compounds. These extracts can be converted into water-soluble powders, granules, pellets, or microspheres.
Modern nano-processing methods enhance the stability, efficacy, and sensory qualities of these materials, protecting them from degradation caused by heat, light, and oxygen over time.

Advantages:

• Preservation of natural and botanical properties against environmental damage
• Controlled and targeted release of active ingredients
• A wide range of formulations adaptable to various needs

Formulation Development and Preparation of PNF Documentation

In the cosmetics and personal care industry, PNF (Product Information File) documentation plays a crucial role in ensuring compliance with international standards and consumer safety. Services include preparing and completing all necessary documentation tailored to each product, in accordance with global regulatory and health requirements.

Advantages:

• Compliance with international cosmetic safety standards
• Assurance of consumer health and product safety
• Structured production planning based on legal documentation

Stabilization and Preservation of Unstable Active Ingredients

Active ingredients such as vitamins, antioxidants, and certain plant extracts are often sensitive to environmental factors. Through nanotechnology, these materials can be stabilized and protected from oxidation, light degradation, and temperature fluctuations. Encapsulation ensures long-lasting efficacy and improved product shelf life.

Advantages:

• Long-term stability of sensitive active ingredients
• Preservation of functional properties through protective coatings
• Prevention of physical and chemical degradation over time

Nano Engineering Services in the Food Industry

In this section, specialized services are provided for optimizing food processes and products through nanotechnology and active ingredient encapsulation. These technologies play a significant role in improving the quality, stability, and efficiency of food products such as dairy, beverages, snacks, and bakery items.
The main goal is to enhance nutritional value, preserve bioactive properties, and optimize production processes.

Fortification and Functionalization with Microencapsulated Micronutrients

Using nanoencapsulation, various micronutrients — including vitamins, minerals, proteins, and antioxidants — are incorporated into different food products such as dairy, energy drinks, snacks, and flour-based items.
This approach allows nutrients to be released in a controlled and targeted manner, protecting them from adverse environmental factors such as heat and humidity.

Advantages:

• Enhanced stability of nutrients against environmental stress
• Improved efficiency of active ingredients during production
• Reduced nutrient loss during processing and storage

Improving Quality, Stability, and Shelf Life of Food Products

Nanoencapsulation technologies are applied in pasteurization and sterilization processes to enhance product quality and shelf life. These techniques protect sensitive nutrients from heat and oxidation, preserving the nutritional value, taste, and color of foods.

Advantages:

• Extended shelf life without chemical preservatives
• Protection of taste, color, and nutritional value during processing
• Reduced need for artificial additives

Formulation Optimization and Improvement

Through nanotechnology, food formulations are optimized to improve both nutritional and functional properties.
These methods address production challenges by refining ingredient composition, improving bioavailability, and enhancing process efficiency.

Advantages:

• Improved functionality of raw materials
• Optimized production processes for higher quality outcomes
• Reduced production costs

Conversion of Fats and Oils into Water-Soluble Powders

Nanoencapsulation enables the transformation of fats and oils into water-soluble powders, allowing their use in beverages and food products with enhanced solubility and absorption.

Advantages:

• Increased solubility of fats and oils in water
• Reduced energy and material waste
• Improved bioavailability and usability in food production

Enhancement of Flavor, Color, and Aroma

Using nanotechnology, flavors, colorants, and aromas are released in a controlled and stable manner within food products.
These nano-formulations extend the shelf life of sensory properties and minimize unwanted changes during production and storage.

Advantages:

• Extended stability of flavors and colors
• Preservation of aroma and sensory quality
• Reduced need for synthetic additives

Custom Research and Development Projects

Customized R&D services are available to support innovation and optimization in food formulations.
These projects include developing new processes or improving existing products through the use of advanced nanotechnologies.

Advantages:

• Support for development of specialized, unique food products
• Utilization of cutting-edge scientific research for process optimization
• Tailored formulations designed to meet market demands

Production of Flavors and Colorants in Liquid, Powder, Granule, Pellet, and Microsphere Forms

Flavors and colorants are produced using nanoencapsulation in various forms such as liquids, powders, granules, and microspheres.
This technology allows precise control over flavor and color release, making it particularly useful for packaged and processed foods.

Advantages:

• Gradual and controlled release of flavor and color
• Improved control over sensory attributes
• Extended flavor and color stability during storage

Development of Innovative and Knowledge-Based Food Products

Through advanced scientific expertise and nanotechnology, innovative and specialized food products are developed with unique functional and nutritional characteristics.
These solutions address specific health and dietary needs while supporting sustainable food innovation.

Advantages:

• Development of unique, science-based food products
• Advanced technological solutions for modern nutrition
• Addressing specialized market and consumer needs

Knowledge-Based Product Development Services

Knowledge-based processes are applied to transform traditional food products into innovative, high-performance ones through nanotechnology.
These services include formulation optimization, process improvement, and overall product quality enhancement.

Advantages:

• Optimization of existing products using advanced technologies
• Enhanced product quality for global market access
• Increased competitiveness in domestic and international markets

Nano Engineering Services in Livestock, Poultry, and Aquatic Industries

By utilizing nanotechnology and encapsulation of active ingredients, innovative solutions are provided for the livestock, poultry, and aquaculture industries. These services are designed to enhance efficiency, optimize nutritional and therapeutic processes, reduce resource waste, and improve animal health.

Production of Smart Coated and Controlled-Release Feed Additives (SMART)

In this process, vitamins, proteins, probiotics, amino acids, and minerals are produced using nanoencapsulation and polymer-based nanocoatings. These coatings are specifically designed to ensure controlled and intelligent release of active ingredients in the digestive system of animals. The products protect sensitive nutrients against heat, moisture, and unfavorable pH conditions, thereby improving their stability and bioavailability.

Advantages:

• Controlled and targeted release of active ingredients
• Protection of nutrients against harsh environmental conditions such as temperature and humidity
• Enhanced absorption and improved nutritional efficiency

Production of Herbal Extracts and Essential Oils

Herbal extracts and essential oils are produced using advanced extraction methods such as Supercritical CO₂ Extraction. This method preserves the bioactive compounds and converts them into forms such as water-soluble powders, granules, pellets, or microspheres. Due to their antibacterial, antiviral, and anti-inflammatory properties, these extracts and oils support gut health and strengthen the immune system of animals.

Advantages:

• Preservation of bioactive compounds through advanced extraction techniques
• Use of natural additives to reduce dependence on synthetic chemicals
• Improved nutrient absorption and transport via nanoformulations

Conversion of Fats and Oils into Water-Soluble Powders

Nanoencapsulation technology is applied to convert fats and oils into water-soluble powders. This process utilizes hydrophilic matrices to encapsulate fat-based compounds into powder forms that easily dissolve in water. As a result, lipids are efficiently absorbed in the digestive system, reducing energy loss and unwanted physical alterations.

Advantages:

• Increased absorption of fats in the digestive system
• Conversion of fat-based materials into feed-compatible forms
• Reduced nutrient and energy loss during production processes

Feed Additives for Livestock, Poultry, and Aquaculture

Using nanotechnology and enzyme-based systems, probiotic and enzymatic feed additives are developed to enhance digestion and nutrient bioavailability. These additives contribute to improved gut health, better feed conversion ratio (FCR), and reduced disease incidence.

Advantages:

• Improved feed efficiency through enhanced digestibility and absorption
• Reduced need for antibiotics and synthetic drugs
• Strengthened immune system and lower disease risk in livestock and poultry

Floating and Slow-Release Formulation for Aquatic Feed

Aquatic feeds are designed with floating and slow-release formulations using nanopolymer materials. These feeds remain longer on the water surface and release nutrients gradually, ensuring optimal nutrient absorption while minimizing water contamination and feed wastage.

Advantages:

• Gradual nutrient release for enhanced absorption by aquatic species
• Reduced feed waste and environmental impact
• Maintained water quality and prevention of pollution

Enhanced Stability and Shelf Life of Feed Materials

Nanotechnology is used to increase the stability of feed ingredients against heat shocks and cooking processes by employing nanoparticles and protective coatings. This approach is particularly effective in ready-to-feed and supplementary animal diets, helping to preserve nutrients and ensure efficient nutrient delivery.

Advantages:

• Preservation of nutritional properties under various production conditions
• Extended shelf life and reduced feed losses
• Optimal resource utilization and waste reduction

Veterinary Pharmaceuticals for Livestock, Poultry, and Aquatic Animals

Nanotechnology is applied to develop veterinary drugs, especially vaccine adjuvants, using natural nanoparticles such as chitosan. This technology improves drug bioavailability and therapeutic efficacy. Additionally, plant-based and natural formulations are designed to minimize side effects while maintaining high effectiveness.

Advantages:

• Enhanced efficacy of veterinary drugs and vaccines
• Reduced side effects of chemical medications
• Strengthened immune response and reduced dependence on synthetic drugs

Toxin and Mycotoxin Removal Using Nanotechnology

Using nanotechnology and nanosorbents, toxins and mycotoxins are removed from animal feed. This process ensures that livestock and poultry are protected from harmful contaminants, maintaining both animal health and the quality of animal products.

Advantages:

• Effective removal of toxins and mycotoxins from feed
• Improved feed safety and reduced disease risks
• Preservation of animal health and product quality

High-Value Product Development from Slaughterhouse By-Products

Through advanced processing and nanoencapsulation technologies, slaughterhouse by-products such as skin, bone, and fat are converted into high-value materials. These processes promote optimal resource utilization, waste reduction, and sustainable production.

Advantages:

• Improved utilization of slaughterhouse by-products
• Production of high-quality, value-added materials
• Reduced production costs and environmental impact