Pharmaceutical Industry

Table of contents

Nano Engineering Services in the Pharmaceutical Industry


At Asr Nano, by leveraging advanced nanotechnology and modern methods such as micro- and nano-encapsulation, liposomes, and phytosomes, we provide specialized and efficient solutions in the pharmaceutical industry. These services are designed to enhance therapeutic effectiveness, improve drug performance, reduce side effects, and optimize production processes.

Offering Modern Drug Delivery Methods and Systems
We utilize liposomal, phytosomal, and exosomal technologies for slow and controlled drug release to increase bioavailability and reduce side effects. These methods allow gradual drug release, improving therapeutic outcomes.
Reducing side effects and increasing bioavailability: Iron salts – reduce gastrointestinal side effects and tooth discoloration while increasing bioavailability; Curcumin – increase bioavailability, stability, and water solubility; Milk thistle extract – increase bioavailability, stability, and water solubility; controlled, targeted, and intelligent release of active ingredients; masking unpleasant tastes and odors; facilitating formulation of active ingredients; converting insoluble substances such as BCAAs, NMN, Minoxidil, Sulforaphane, Adenosine, Vitamins, Calcium, Zinc, Probiotics, Amino Acids.

Advantages:

  • Controlled drug release for longer therapeutic effects
  • Reduction of side effects through gradual release
  • Increased treatment accuracy via advanced drug delivery technologies

Masking Unpleasant Drug Taste and Odor


Using nano-encapsulation technology, unpleasant tastes and odors of drugs are masked to prevent oral and gastrointestinal irritation and make drug consumption easier. This approach addresses the unpleasant taste of caffeine products, B vitamins, azithromycin, omega-3: increasing stability, reducing odor, and producing water-soluble powders (e.g., Ibuprofen, Paracetamol, B vitamins).

Advantages:

  • Eliminates unpleasant tastes and odors
  • Improves patient compliance and ease of use
  • Increases patient acceptance of medications

Uniform Dispersion of Insoluble Substances in Aqueous and Organic Media
Nano-technologies are employed to achieve uniform dispersion of insoluble substances in aqueous and organic systems. This process ensures active ingredients are evenly distributed in formulations, enhancing drug efficacy. Examples include curcumin (poor water solubility), all oils and plant essential oils, omega-3.

Advantages:

  • Uniform distribution of active ingredients
  • Increased solubility and efficacy of active compounds
  • Improved stability of insoluble drugs

Adjuvant Formulations for Vaccines Based on Natural Nanoparticles


Using natural nanoparticles such as chitosan, adjuvant formulations are designed to enhance immune responses and increase vaccine effectiveness.

Advantages:

  • Enhanced immune response with natural nanoparticles
  • Reduced vaccine doses with improved efficacy
  • Decreased vaccine side effects

Green and Enzymatic Synthesis of Active Ingredients
Green and enzymatic synthesis of pharmaceutical active ingredients is performed to produce natural compounds and reduce contaminants in the production process. These methods reduce costs and increase productivity in active ingredient manufacturing.

Advantages:

  • Production of drugs using green, pollution-free methods
  • Cost reduction through enzymatic processes
  • Maintenance of active ingredient stability during production

Formulation and Preparation of CTD


Asr Nano offers formulation services for new drugs and preparation of the Common Technical Document (CTD) to facilitate the drug registration process from development to end-of-life. This process accelerates regulatory approvals and market entry.

Advantages:

  • Simplified drug registration process
  • Compliance with international regulations
  • Faster market availability of drugs

Technology Transfer and Scale-Up from Laboratory to Industrial Production
Scale-up services from lab to industrial scale using nanotechnology enhance drug production at large scale without quality loss. This process reduces costs and increases production efficiency.

Advantages:

  • Optimal resource utilization
  • Increased production volume while maintaining quality
  • Reduced production costs at industrial scale

Increasing Drug Bioavailability


Through nanotechnology and active ingredient encapsulation, drug bioavailability is enhanced, enabling better absorption in the body. This process improves therapeutic efficacy and reduces dosage requirements.

Advantages:

  • Enhanced drug bioavailability
  • Reduced dosage and side effects
  • Improved treatment effectiveness

Providing Knowledge-Based Product Development Services
Asr Nano offers knowledge-based services to enhance the quality and efficacy of pharmaceutical products and vaccines. These services include R&D, innovation in formulations, synthesis, extraction, and processing of active ingredients using new and efficient methods.

Advantages:

  • Improved quality of pharmaceutical products
  • Support for innovative research processes
  • Facilitation of commercialization of knowledge-based products